Searchable abstracts of presentations at key conferences in endocrinology

ea0086oc5.3 | Metabolism, Obesity and Diabetes | SFEBES2022

Normothermic machine liver perfusion as a tool to study human androgen metabolism

Anthony Amarah , Clarke George , Schiffer Lina , Fan Yiyu , Hawley James , Shaheen Fozia , Hann Angus , Taylor Angela , Afford Simon , Arlt Wiebke

Background: In women, androgen excess is associated with an increased risk of non-alcoholic fatty liver disease (NAFLD). Androgen precursors are released from the adrenal gland and converted to active androgens in peripheral tissues including adipose tissue. Although the liver plays a key role in all metabolic processes in the body, its involvement in androgen metabolism is yet to be explored. Here, we describe the investigation of androgen metabolism in human liver using norm...